STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)    
Predicted Functional Partners:
MAP2K1
Mitogen-activated protein kinase kinase 1.
   
0.995
RPS6KA5
Ribosomal protein S6 kinase alpha-5.
   
0.989
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
   
0.988
RPS6KA1
Ribosomal protein S6 kinase.
   
0.987
SMAD2
Mothers against decapentaplegic homolog.
   
 0.979
PTPN7
Protein tyrosine phosphatase, non-receptor type 7.
    
 0.979
FOS
Proto-oncogene c-Fos.
   
 0.975
MAP2K3
Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
  
0.973
RPS6KA3
Ribosomal protein S6 kinase alpha-3.
   
0.973
KRAS
GTPase KRas.
   
 0.973
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.