Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEV67434.1Putative hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold. (307 aa)    
Predicted Functional Partners:
AEV69231.1
acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme.
 
 
 0.927
AEV68465.1
Polyketide synthase family protein; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain.
  
 0.917
AEV67292.1
Non-ribosomal peptide synthase; PFAM: Glycosyltransferase family 28 N-terminal domain; Condensation domain; manually curated.
 
 
 0.735
AEV69983.1
Putative hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold.
  
     0.701
AEV67271.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.647
AEV67317.1
NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family.
  
 
 0.577
AEV68492.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
 
  
 0.575
AEV69225.1
PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; non-ribosomal peptide synthase domain TIGR01720; manually curated; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.572
birA
biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.474
AEV67290.1
Penicillin-binding protein, beta-lactamase class C; PFAM: Beta-lactamase.
  
   
 0.458
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.