STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV67551.1PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. (176 aa)    
Predicted Functional Partners:
AEV68658.1
Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.939
ispH
(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.650
AEV67552.1
PFAM: Aromatic prenyltransferase Orf2.
       0.639
AEV68693.1
PFAM: Protein of unknown function (DUF3237); Dockerin type I repeat.
   
  
 0.620
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
   
 
 0.542
AEV68492.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
     
 0.476
AEV69560.1
Hypothetical protein.
  
     0.471
AEV68465.1
Polyketide synthase family protein; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain.
  
  
 0.457
AEV69231.1
acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme.
   
  
 0.432
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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