Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEV67611.1PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. (857 aa)    
Predicted Functional Partners:
AEV67271.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.981
AEV68625.1
PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.961
AEV68844.1
HD-GYP domain-containing protein; PFAM: HD domain.
 
 
 
 0.915
AEV68840.1
PFAM: GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.860
AEV68018.1
PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
 
0.825
AEV69436.1
Uncharacterized domain HDIG-containing protein; PFAM: Domain of unknown function (DUF3369); HD domain; Response regulator receiver domain; TIGRFAM: uncharacterized domain HDIG.
 
 
 0.801
AEV68185.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 
 0.775
AEV69920.1
PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 
0.761
AEV68676.1
PFAM: HD domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.754
AEV69760.1
PFAM: HD domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; manually curated.
 
 
0.752
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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