| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEV67317.1 | AEV70487.1 | Clocl_0608 | Clocl_4051 | NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain. | 0.569 |
| AEV67317.1 | guaA | Clocl_0608 | Clocl_3083 | NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.672 |
| AEV67317.1 | hppA | Clocl_0608 | Clocl_0965 | NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family. | Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.484 |
| AEV67317.1 | nnrE | Clocl_0608 | Clocl_0405 | NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family. | yjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...] | 0.612 |
| AEV67640.1 | AEV67641.1 | Clocl_0963 | Clocl_0964 | Putative membrane protein; PFAM: Branched-chain amino acid transport protein (AzlD). | Putative branched-chain amino acid permease (azaleucine resistance); PFAM: AzlC protein. | 0.976 |
| AEV67640.1 | hppA | Clocl_0963 | Clocl_0965 | Putative membrane protein; PFAM: Branched-chain amino acid transport protein (AzlD). | Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.418 |
| AEV67641.1 | AEV67640.1 | Clocl_0964 | Clocl_0963 | Putative branched-chain amino acid permease (azaleucine resistance); PFAM: AzlC protein. | Putative membrane protein; PFAM: Branched-chain amino acid transport protein (AzlD). | 0.976 |
| AEV67641.1 | hppA | Clocl_0964 | Clocl_0965 | Putative branched-chain amino acid permease (azaleucine resistance); PFAM: AzlC protein. | Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.418 |
| AEV67799.1 | guaA | Clocl_1124 | Clocl_3083 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.693 |
| AEV67799.1 | hppA | Clocl_1124 | Clocl_0965 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.411 |
| AEV67799.1 | ribBA | Clocl_1124 | Clocl_1126 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| AEV70487.1 | AEV67317.1 | Clocl_4051 | Clocl_0608 | Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain. | NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.569 |
| AEV70487.1 | guaA | Clocl_4051 | Clocl_3083 | Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.706 |
| AEV70487.1 | hppA | Clocl_4051 | Clocl_0965 | Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain. | Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.417 |
| AEV70487.1 | nnrE | Clocl_4051 | Clocl_0405 | Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain. | yjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...] | 0.448 |
| guaA | AEV67317.1 | Clocl_3083 | Clocl_0608 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family. | 0.672 |
| guaA | AEV67799.1 | Clocl_3083 | Clocl_1124 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.693 |
| guaA | AEV70487.1 | Clocl_3083 | Clocl_4051 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inorganic pyrophosphatase/exopolyphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain. | 0.706 |
| guaA | hppA | Clocl_3083 | Clocl_0965 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inorganic pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.405 |
| guaA | ribBA | Clocl_3083 | Clocl_1126 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.782 |