STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (115 aa)    
Predicted Functional Partners:
AEV67661.1
Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
 
 0.986
AEV67629.1
Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase.
 
 
 0.967
AEV67664.1
PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.944
AEV67662.1
(NiFe) hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; Belongs to the carbamoyltransferase HypF family.
 
   
 0.939
AEV67658.1
Ni,Fe-hydrogenase III large subunit; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase; Belongs to the complex I 49 kDa subunit family.
 
 
 0.917
AEV67663.1
PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
  
 0.911
AEV67665.1
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
  
 0.908
AEV67659.1
NADH:ubiquinone oxidoreductase chain I-like protein; PFAM: 4Fe-4S binding domain.
 
  
 0.866
AEV67654.1
NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter, MnhA subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.
 
   
 0.827
AEV67657.1
NADH:ubiquinone oxidoreductase 27 kD subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
 
    0.792
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.