STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV68347.1PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus. (430 aa)    
Predicted Functional Partners:
AEV70409.1
Putative phosphatase, C-terminal domain of histone macro H2A1 like protein; PFAM: Macro domain.
      0.692
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.663
AEV66762.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.627
cinA
PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.
     
 0.620
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.600
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.584
AEV68346.1
ACT domain-containing protein; PFAM: ACT domain.
       0.531
AEV70464.1
DNA polymerase III, delta'' subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau.
   
 
 0.453
AEV68345.1
Coenzyme F390 synthetase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
       0.441
AEV68130.1
tRNA nucleotidyltransferase/poly(A) polymerase; PFAM: DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.438
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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