Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEV68775.1PFAM: PRC-barrel domain; TIGRFAM: sporulation protein, YlmC/YmxH family. (89 aa)    
Predicted Functional Partners:
AEV68776.1
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.894
AEV68777.1
RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.864
AEV67815.1
PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
  
    0.818
AEV67342.1
PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
 
     0.805
AEV68778.1
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
   
 0.799
AEV68051.1
Protease subunit of ATP-dependent protease; PFAM: Clp protease.
 
   
 0.793
AEV69086.1
PFAM: Stage IV sporulation protein A (spore_IV_A); TIGRFAM: stage IV sporulation protein A.
 
     0.782
AEV67054.1
PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
  
 0.774
AEV68672.1
TIGRFAM: stage III sporulation protein AA.
  
    0.773
AEV67816.1
PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
    0.772
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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