STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pdxSPyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa)    
Predicted Functional Partners:
AEV68791.1
Pyridoxal phosphate synthase yaaE subunit; PFAM: SNO glutamine amidotransferase family; TIGRFAM: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2.
 0.999
AEV67824.1
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.834
rbsK
Sugar kinase, ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
     
 0.832
AEV67143.1
Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain.
    
  0.806
AEV67144.1
Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
  0.806
AEV67689.1
Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain.
    
  0.806
AEV67690.1
Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
  0.806
AEV67914.1
Transketolase, alpha subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
  0.806
AEV67915.1
Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain.
    
  0.806
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
  0.805
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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