STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV68795.1O-acetylhomoserine sulfhydrolase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. (426 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.985
AEV68603.1
PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase; methylmalonyl-CoA mutase C-terminal domain.
  
 
 0.970
AEV69919.1
Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
 
 
0.942
AEV68794.1
Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.933
AEV69287.1
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II.
   
 0.928
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.918
AEV69434.1
PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase.
 
 
 0.915
AEV68892.1
Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.850
AEV69915.1
Sulfate adenylyltransferase subunit 1, adenylylsulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.719
AEV68604.1
PFAM: Vitamin B12 dependent methionine synthase, activation domain.
  
 
 0.622
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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