STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV68841.1PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA. (737 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.960
AEV68783.1
Cell division septal protein; PFAM: POTRA domain, FtsQ-type.
  
 
 0.912
AEV70492.1
Cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: cyanophycin synthetase; Belongs to the MurCDEF family.
  
  
 0.906
AEV68641.1
Hypothetical protein; Manually curated.
   
 
 0.899
AEV69000.1
Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: stage V sporulation protein D; manually curated.
  
 
 0.704
AEV68555.1
Flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN; manually curated.
 
   
 0.700
nth
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.690
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
 
 0.669
AEV68092.1
PFAM: Uncharacterized protein conserved in bacteria (DUF2225).
 
     0.663
AEV70465.1
PFAM: Protein of unknown function (DUF327).
  
     0.656
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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