STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV69086.1PFAM: Stage IV sporulation protein A (spore_IV_A); TIGRFAM: stage IV sporulation protein A. (535 aa)    
Predicted Functional Partners:
AEV68672.1
TIGRFAM: stage III sporulation protein AA.
  
  
 0.895
AEV67054.1
PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
  
 0.892
AEV67049.1
PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D; manually curated.
  
  
 0.873
AEV68666.1
TIGRFAM: stage III sporulation protein AG.
  
  
 0.867
AEV68669.1
PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD.
  
    0.866
AEV69328.1
PFAM: Stage II sporulation protein P (SpoIIP); TIGRFAM: stage II sporulation protein P.
 
   
 0.866
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.862
AEV67342.1
PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
   
 0.861
AEV68631.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.853
gpr
GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.851
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.