STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gprGPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (334 aa)    
Predicted Functional Partners:
AEV67816.1
PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
  
 0.922
AEV67815.1
PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
  
  
 0.888
AEV69086.1
PFAM: Stage IV sporulation protein A (spore_IV_A); TIGRFAM: stage IV sporulation protein A.
  
   
 0.851
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.847
AEV69111.1
PFAM: Small, acid-soluble spore proteins, alpha/beta type.
  
  
 0.847
AEV68631.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.833
AEV69800.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.820
AEV68632.1
Stage IV sporulation protein B; PFAM: SpoIVB peptidase S55; PDZ domain (Also known as DHR or GLGF); TIGRFAM: stage IV sporulation protein B; manually curated.
  
    0.818
AEV67068.1
Stage V sporulation protein T; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T.
  
  
 0.799
AEV70547.1
PFAM: Protein of unknown function (DUF1256); TIGRFAM: putative sporulation protein YyaC.
  
  
 0.794
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.