STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queEOrganic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (209 aa)    
Predicted Functional Partners:
AEV69782.1
Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
 
 
 0.998
queC
preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
 
 0.998
AEV69779.1
PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
       0.791
AEV69780.1
PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
       0.791
folE
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
  
 0.757
AEV67423.1
Ribonucleoside-triphosphate reductase class III catalytic subunit; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
  
 
 0.724
AEV68337.1
Glycine radical enzyme, YjjI family; PFAM: Protein of unknown function (DUF3029); TIGRFAM: glycine radical enzyme, YjjI family.
  
 
 0.724
AEV68598.1
Ribonucleoside-triphosphate reductase class III catalytic subunit; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
  
 
 0.724
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.713
AEV69785.1
Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
    0.680
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
Server load: low (20%) [HD]