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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV69835.1Hypothetical protein. (311 aa)    
Predicted Functional Partners:
AEV69680.1
Chromosome segregation ATPase; Manually curated.
  
   
 0.707
AEV69682.1
Hypothetical protein.
  
     0.689
AEV70360.1
Dockerin-like protein; PFAM: Dockerin type I repeat.
  
     0.667
AEV68387.1
Uncharacterized protein containing chitin-binding domain type 3; PFAM: S-layer homology domain; PKD domain; Fibronectin type III domain.
 
     0.633
AEV69446.1
Hypothetical protein; PFAM: Acyltransferase family; manually curated.
  
     0.631
AEV69681.1
Hypothetical protein.
  
     0.626
AEV69790.1
Hypothetical protein.
 
   0.603
AEV67576.1
PFAM: Copper amine oxidase N-terminal domain.
  
     0.589
AEV69727.1
PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller.
  
  
 0.587
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.587
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
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