| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEV68114.1 | AEV69273.1 | Clocl_1465 | Clocl_2716 | ADP-ribose pyrophosphatase; PFAM: NUDIX domain. | NTP pyrophosphohydrolase; PFAM: NUDIX domain. | 0.923 |
| AEV68114.1 | thiM | Clocl_1465 | Clocl_3526 | ADP-ribose pyrophosphatase; PFAM: NUDIX domain. | Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.900 |
| AEV68206.1 | AEV69117.1 | Clocl_1570 | Clocl_2547 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | 0.724 |
| AEV68206.1 | AEV70002.1 | Clocl_1570 | Clocl_3523 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. | 0.458 |
| AEV68206.1 | thiC | Clocl_1570 | Clocl_2542 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.839 |
| AEV68206.1 | thiE | Clocl_1570 | Clocl_2543 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.674 |
| AEV68206.1 | thiE-2 | Clocl_1570 | Clocl_3525 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.674 |
| AEV68206.1 | thiG | Clocl_1570 | Clocl_2546 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | Putative enzyme of thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.991 |
| AEV68206.1 | thiM | Clocl_1570 | Clocl_3526 | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.473 |
| AEV69117.1 | AEV68206.1 | Clocl_2547 | Clocl_1570 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | 0.724 |
| AEV69117.1 | AEV70002.1 | Clocl_2547 | Clocl_3523 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. | 0.898 |
| AEV69117.1 | thiC | Clocl_2547 | Clocl_2542 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.962 |
| AEV69117.1 | thiE | Clocl_2547 | Clocl_2543 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.933 |
| AEV69117.1 | thiE-2 | Clocl_2547 | Clocl_3525 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.819 |
| AEV69117.1 | thiG | Clocl_2547 | Clocl_2546 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | Putative enzyme of thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.998 |
| AEV69117.1 | thiM | Clocl_2547 | Clocl_3526 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.540 |
| AEV69273.1 | AEV68114.1 | Clocl_2716 | Clocl_1465 | NTP pyrophosphohydrolase; PFAM: NUDIX domain. | ADP-ribose pyrophosphatase; PFAM: NUDIX domain. | 0.923 |
| AEV69273.1 | thiM | Clocl_2716 | Clocl_3526 | NTP pyrophosphohydrolase; PFAM: NUDIX domain. | Hydroxyethylthiazole kinase, sugar kinase family; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.900 |
| AEV70002.1 | AEV68206.1 | Clocl_3523 | Clocl_1570 | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. | Iron-only hydrogenase maturation protein HydG; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH. | 0.458 |
| AEV70002.1 | AEV69117.1 | Clocl_3523 | Clocl_2547 | PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. | 0.898 |
