Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEV70446.1Putative stress-responsive transcriptional regulator; PFAM: PspC domain. (66 aa)    
Predicted Functional Partners:
AEV66797.1
Phage shock protein A (IM30), suppresses sigma54-dependent transcription.
  
 
 0.910
AEV68625.1
PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
   
 
 0.849
AEV67768.1
Putative stress-responsive transcriptional regulator; PFAM: PspC domain; manually curated.
  
     0.773
AEV67271.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
 0.731
AEV70418.1
PFAM: Membrane protein of unknown function.
  
    0.701
AEV68111.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; manually curated.
   
 
 0.620
AEV67025.1
Hypothetical protein.
  
  
 0.548
AEV68495.1
Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin.
   
  
 0.424
AEV68845.1
Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
   
  
 0.424
AEV70579.1
Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
   
  
 0.424
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
Server load: low (20%) [HD]