STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEV70557.1Putative ATPase of the PP-loop superfamily implicated in cell cycle control; PFAM: PP-loop family; Belongs to the TtcA family. (237 aa)    
Predicted Functional Partners:
AEV69117.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
 
 0.759
AEV69288.1
TIGR00268 family protein; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein.
 
    0.626
AEV69231.1
acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme.
  
 
 0.607
AEV70558.1
PFAM: Predicted periplasmic protein (DUF2233).
       0.602
AEV67317.1
NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; DsrE/DsrF-like family; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; TIGRFAM: CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family.
  
  
 0.540
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.538
metG
Protein containing C-terminal region/beta chain of methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.527
mfd
Transcription-repair coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.523
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.523
AEV68465.1
Polyketide synthase family protein; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain.
 
  
 0.503
Your Current Organism:
Hungateiclostridium clariflavum
NCBI taxonomy Id: 720554
Other names: Clostridium clariflavum DSM 19732, Clostridium clariflavum EBR45, H. clariflavum DSM 19732, Hungateiclostridium clariflavum DSM 19732
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.