STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1I7V7B0Uncharacterized protein. (1178 aa)    
Predicted Functional Partners:
A0A1I7V8P3
Suppressor of Ty 6 homolog; May regulate transcriptional elongation by RNA polymerase II.
   
 0.997
LOAG_17357
Transcription elongation factor SPT5.
   
 0.956
A0A1I7VFH9
Uncharacterized protein.
    
 0.947
LOAG_04347
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.943
LOAG_04502
Metallopeptidase family M24 containing protein.
   
 0.931
LOAG_08410
RNA polymerase Rpb3/Rpb11 dimerization domain-containing protein.
    
 0.921
LOAG_04253
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.907
LOAG_06607
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.894
A0A1I7VEB2
Uncharacterized protein.
   
 0.884
LOAG_06832
TPR_REGION domain-containing protein.
   
 0.881
Your Current Organism:
Loa loa
NCBI taxonomy Id: 7209
Other names: L. loa, eye worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.