LOAG_05501 protein (Loa loa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOAG_05501

DAO-2 protein. (349 aa)

Predicted Functional Partners:

A0A1I7VTK5

0.669

A0A1I7VAL4

0.498

LOAG_04774

0.473

A0A1I7VDI2

0.445

LOAG_10012

0.429

LOAG_12973

0.429

LOAG_16774

0.421

A0A1I7VPY6

0.421

LOAG_00942

0.412

LOAG_09049

0.412

Your Current Organism:

Loa loa

NCBI taxonomy Id: 7209
Other names: L. loa, eye worm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I7VAL4	LOAG_05501	A0A1I7VAL4	A0A1I7VF74	Protein kinase domain-containing protein.	DAO-2 protein.	0.498
A0A1I7VDI2	LOAG_05501	A0A1I7VDI2	A0A1I7VF74	CBR-LAG-1 protein.	DAO-2 protein.	0.445
A0A1I7VPY6	A0A1I7VTK5	A0A1I7VPY6	A0A1I7VTK5	GRIP domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.963
A0A1I7VPY6	LOAG_05501	A0A1I7VPY6	A0A1I7VF74	GRIP domain-containing protein.	DAO-2 protein.	0.421
A0A1I7VTK5	A0A1I7VPY6	A0A1I7VTK5	A0A1I7VPY6	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	GRIP domain-containing protein.	0.963
A0A1I7VTK5	LOAG_05501	A0A1I7VTK5	A0A1I7VF74	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	DAO-2 protein.	0.669
A0A1I7VTK5	LOAG_10012	A0A1I7VTK5	A0A1I7VUH5	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.580
A0A1I7VTK5	LOAG_12973	A0A1I7VTK5	A0A1S0TKB0	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.580
A0A1I7VTK5	LOAG_16774	A0A1I7VTK5	A0A1I7V5P5	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	RanBP1 domain-containing protein.	0.992
LOAG_00942	LOAG_05501	A0A1I7VM06	A0A1I7VF74	CULLIN_2 domain-containing protein; Belongs to the cullin family.	DAO-2 protein.	0.412
LOAG_00942	LOAG_09049	A0A1I7VM06	A0A1I7VNR9	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 3; Belongs to the cullin family.	0.778
LOAG_04774	LOAG_05501	A0A1I7VGT3	A0A1I7VF74	DPH-type MB domain-containing protein.	DAO-2 protein.	0.473
LOAG_05501	A0A1I7VAL4	A0A1I7VF74	A0A1I7VAL4	DAO-2 protein.	Protein kinase domain-containing protein.	0.498
LOAG_05501	A0A1I7VDI2	A0A1I7VF74	A0A1I7VDI2	DAO-2 protein.	CBR-LAG-1 protein.	0.445
LOAG_05501	A0A1I7VPY6	A0A1I7VF74	A0A1I7VPY6	DAO-2 protein.	GRIP domain-containing protein.	0.421
LOAG_05501	A0A1I7VTK5	A0A1I7VF74	A0A1I7VTK5	DAO-2 protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.669
LOAG_05501	LOAG_00942	A0A1I7VF74	A0A1I7VM06	DAO-2 protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.412
LOAG_05501	LOAG_04774	A0A1I7VF74	A0A1I7VGT3	DAO-2 protein.	DPH-type MB domain-containing protein.	0.473
LOAG_05501	LOAG_09049	A0A1I7VF74	A0A1I7VNR9	DAO-2 protein.	Cullin 3; Belongs to the cullin family.	0.412
LOAG_05501	LOAG_10012	A0A1I7VF74	A0A1I7VUH5	DAO-2 protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.429