STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOAG_18080CAP-Gly domain-containing protein. (1262 aa)    
Predicted Functional Partners:
LOAG_12430
Uncharacterized protein.
   
 0.967
A0A1I7VEB6
Actin; Belongs to the actin family.
    
 0.940
A0A1I7VJZ6
Dynactin 4.
    
 0.935
LOAG_04904
Cytoplasmic dynein intermediate chain 1.
   
 0.930
LOAG_07944
Beta-centractin.
   
 0.929
A0A1I7V7V4
Uncharacterized protein.
    
 0.920
LOAG_10528
Dynactin 5.
    
 0.916
LOAG_04611
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.892
LOAG_06499
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
   
 0.889
LOAG_10536
Bicaudal-D.
    
 0.878
Your Current Organism:
Loa loa
NCBI taxonomy Id: 7209
Other names: L. loa, eye worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.