STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1I7VGT7Adenosine deaminase. (368 aa)    
Predicted Functional Partners:
A0A1I7VH75
PfkB domain-containing protein.
   
 0.984
A0A1I7V938
Uncharacterized protein.
     
 0.920
A0A1I7VKR8
Uncharacterized protein.
     
 0.920
LOAG_11857
Adenine phosphoribosyltransferase.
   
 0.911
A0A1I7VXY5
Uncharacterized protein.
     
 0.907
A0A1I7VY00
5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.
     
 0.907
A0A1I7V858
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
 0.808
LOAG_01831
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.767
LOAG_16397
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
 
 0.722
LOAG_01139
HAD-superfamily hydrolase.
   
 0.696
Your Current Organism:
Loa loa
NCBI taxonomy Id: 7209
Other names: L. loa, eye worm
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