STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1I7VHT6MUTSd domain-containing protein. (253 aa)    
Predicted Functional Partners:
A0A1I7VJI8
Uncharacterized protein.
   
 0.960
A0A1I7VHQ1
DNA_MISMATCH_REPAIR_2 domain-containing protein.
 
      0.900
LOAG_07794
DNA_mis_repair domain-containing protein.
  
 0.891
A0A1I7VA79
CBR-PMS-2 protein.
  
 0.885
A0A1I7V9J5
Uncharacterized protein.
   
 
 0.832
A0A1I7W3J5
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.812
A0A1I7VKD7
Uncharacterized protein.
   
 0.735
LOAG_11057
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
 0.623
A0A1I7VW22
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.604
A0A1I7VWA7
Uncharacterized protein.
   
 0.595
Your Current Organism:
Loa loa
NCBI taxonomy Id: 7209
Other names: L. loa, eye worm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.