STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOAG_01323Kap beta 3 protein. (1103 aa)    
Predicted Functional Partners:
A0A1I7VW80
Nsp1_C domain-containing protein.
   
 
 0.967
A0A1I7VTK5
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 
 0.929
A0A1I7VV74
ULP_PROTEASE domain-containing protein.
   
 
 0.912
LOAG_04985
Importin N-terminal domain-containing protein.
   
 
 0.899
A0A1I7VH24
RRM domain-containing protein.
   
 
 0.893
A0A1I7VX50
Importin N-terminal domain-containing protein.
   
 
 0.886
LOAG_06358
Uncharacterized protein.
   
 
 0.849
LOAG_10012
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.839
LOAG_12973
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.839
LOAG_18897
Importin-beta domain-containing protein.
   
 
 0.837
Your Current Organism:
Loa loa
NCBI taxonomy Id: 7209
Other names: L. loa, eye worm
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