LOAG_16803 protein (Loa loa) - STRING interaction network

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Score

LOAG_16803

Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (422 aa)

Predicted Functional Partners:

LOAG_16768

0.999

A0A1I7VED8

0.998

LOAG_03295

0.989

LOAG_06771

0.986

A0A1I7W1F4

0.977

A0A1I7VA20

0.974

A0A1I7VPP2

0.974

A0A1I7VG47

0.956

LOAG_17925

0.944

LOAG_00507

0.939

Your Current Organism:

Loa loa

NCBI taxonomy Id: 7209
Other names: L. loa, eye worm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1I7VA20	A0A1I7VED8	A0A1I7VA20	A0A1I7VED8	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Transket_pyr domain-containing protein.	0.983
A0A1I7VA20	A0A1I7VG47	A0A1I7VA20	A0A1I7VG47	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.685
A0A1I7VA20	A0A1I7VPP2	A0A1I7VA20	A0A1I7VPP2	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.940
A0A1I7VA20	A0A1I7W1F4	A0A1I7VA20	A0A1I7W1F4	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.891
A0A1I7VA20	LOAG_00507	A0A1I7VA20	A0A1I7VNE3	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.576
A0A1I7VA20	LOAG_03295	A0A1I7VA20	A0A1I7VZX4	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Citrate synthase; Belongs to the citrate synthase family.	0.789
A0A1I7VA20	LOAG_06771	A0A1I7VA20	A0A1I7VMI3	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.999
A0A1I7VA20	LOAG_16768	A0A1I7VA20	A0A1I7VMY9	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.991
A0A1I7VA20	LOAG_16803	A0A1I7VA20	A0A1I7W0B7	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.974
A0A1I7VA20	LOAG_17925	A0A1I7VA20	A0A1I7V8N4	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.664
A0A1I7VED8	A0A1I7VA20	A0A1I7VED8	A0A1I7VA20	Transket_pyr domain-containing protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.983
A0A1I7VED8	A0A1I7VG47	A0A1I7VED8	A0A1I7VG47	Transket_pyr domain-containing protein.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.995
A0A1I7VED8	A0A1I7VPP2	A0A1I7VED8	A0A1I7VPP2	Transket_pyr domain-containing protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.983
A0A1I7VED8	A0A1I7W1F4	A0A1I7VED8	A0A1I7W1F4	Transket_pyr domain-containing protein.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.930
A0A1I7VED8	LOAG_00507	A0A1I7VED8	A0A1I7VNE3	Transket_pyr domain-containing protein.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.984
A0A1I7VED8	LOAG_03295	A0A1I7VED8	A0A1I7VZX4	Transket_pyr domain-containing protein.	Citrate synthase; Belongs to the citrate synthase family.	0.972
A0A1I7VED8	LOAG_06771	A0A1I7VED8	A0A1I7VMI3	Transket_pyr domain-containing protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.992
A0A1I7VED8	LOAG_16768	A0A1I7VED8	A0A1I7VMY9	Transket_pyr domain-containing protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.968
A0A1I7VED8	LOAG_16803	A0A1I7VED8	A0A1I7W0B7	Transket_pyr domain-containing protein.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.998
A0A1I7VED8	LOAG_17925	A0A1I7VED8	A0A1I7V8N4	Transket_pyr domain-containing protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.987