STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DgriGH13012GH13012; Belongs to the argonaute family. (636 aa)    
Predicted Functional Partners:
DgriGH10973
GH10973; Belongs to the argonaute family.
  
0.959
DgriGH10762
GH10762; Belongs to the argonaute family.
  
0.930
DgriGH21857
GH21857.
   
 0.894
DgriGH17400
GH17400.
   
 0.768
spn-E
Probable ATP-dependent RNA helicase spindle-E; Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons. Involved in the repression of LTR retrotransposon copia. Also involved in telomere regulation by repres [...]
   
 0.736
DgriGH18351
GH18351.
   
 0.555
DgriGH18349
GH18349.
   
 0.555
DgriGH22875
GH22875; Belongs to the DEAD box helicase family.
   
 0.550
DgriGH13085
GH13085.
   
 0.510
DgriGH13819
GH13819.
   
 
 0.501
Your Current Organism:
Drosophila grimshawi
NCBI taxonomy Id: 7222
Other names: D. grimshawi, Idiomyia grimshawi
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.