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su(s) protein (fruit fly) - STRING interaction network
"su(s)" - RNA binding in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
su(s)RNA binding; Affects the transcript levels of those alleles that it suppresses. May be involved in influencing complex assembly on cryptic 5’-splice sites or nuclear RNA export; binds RNA preferentially at a sequence that resembles a cryptic 5’-splice site (in vitro) (1325 aa)    
Predicted Functional Partners:
IntS11
Integrator 11 (597 aa)
     
  0.996
su(f)
Suppressor of forked; Essential protein, may play a role in mRNA production or stability (765 aa)
     
  0.990
Cpsf160
Protein binding; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity) (1455 aa)
     
  0.987
Cpsf100
mRNA 3’-UTR binding; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3’-ends of polyadenylated and histone pre-mRNA (756 aa)
     
  0.986
CstF-50
CstF-50 (424 aa)
     
  0.981
hrg
Hiiragi (827 aa)
     
  0.977
IntS9
Integrator 9 (654 aa)
     
  0.977
CG1109
CG1109, isoform A (807 aa)
     
 
  0.967
Fip1
Protein binding (701 aa)
     
 
  0.966
Cpsf73
DNA binding; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity and functions as mRNA 3’-end-processing endonuclease. Required for the cotranscriptional processing of 3’-ends of polyadenylated and histone pre-mRNA (684 aa)
     
  0.964
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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