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tw protein (fruit fly) - STRING interaction network
"tw" - Protein O-mannosyltransferase 2 in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
twProtein O-mannosyltransferase 2; Rt/POMT1 and tw/POMT2 function as a protein O- mannosyltransferase in association with each other to generate and maintain normal muscle development (765 aa)    
Predicted Functional Partners:
rt
Rotated abdomen; Rt/POMT1 and tw/POMT2 function as a protein O- mannosyltransferase in association with each other to generate and maintain normal muscle development (886 aa)
     
 
0.922
Dg
Dystroglycan (1262 aa)
     
   
  0.538
oxt
Peptide O-xylosyltransferase; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (876 aa)
       
 
  0.515
CG1129
Mannose-1-phosphate guanylyltransferase activity (369 aa)
     
 
  0.509
CG15651
FI03527p (572 aa)
           
  0.497
CG11306
Alpha-1,2-mannosyltransferase activity (475 aa)
       
 
  0.443
gny
Garnysstan; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. Involved in cuticle differentiation (475 aa)
     
 
  0.429
cbs
Centrosomin’s beautiful sister (611 aa)
           
  0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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