| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG11109 | CG1434 | FBpp0078203 | FBpp0308524 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | 0.824 |
| CG11109 | CG3021 | FBpp0078203 | FBpp0070168 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | 0.807 |
| CG11109 | CG32281 | FBpp0078203 | FBpp0072898 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family. | 0.730 |
| CG11109 | CG34140 | FBpp0078203 | FBpp0110275 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: tRNA pseudouridine synthesis. | 0.708 |
| CG11109 | CG3434 | FBpp0078203 | FBpp0076201 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.822 |
| CG11109 | CG3645 | FBpp0078203 | FBpp0307923 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | MIP22167p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA processing; oxidation-reduction process. | 0.898 |
| CG11109 | CG3808 | FBpp0078203 | FBpp0074808 | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | RRM domain-containing protein; Nucleic acid binding; RNA methyltransferase activity; mRNA binding. It is involved in the biological process described with: RNA processing; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.603 |
| CG1434 | CG11109 | FBpp0308524 | FBpp0078203 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.824 |
| CG1434 | CG3021 | FBpp0308524 | FBpp0070168 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | 0.817 |
| CG1434 | CG32281 | FBpp0308524 | FBpp0072898 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family. | 0.926 |
| CG1434 | CG34140 | FBpp0308524 | FBpp0110275 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | Pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: tRNA pseudouridine synthesis. | 0.692 |
| CG1434 | CG3434 | FBpp0308524 | FBpp0076201 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.770 |
| CG1434 | CG3645 | FBpp0308524 | FBpp0307923 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | MIP22167p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA processing; oxidation-reduction process. | 0.781 |
| CG1434 | CG3808 | FBpp0308524 | FBpp0074808 | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | RRM domain-containing protein; Nucleic acid binding; RNA methyltransferase activity; mRNA binding. It is involved in the biological process described with: RNA processing; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.492 |
| CG18528 | CG3021 | FBpp0084012 | FBpp0070168 | RE57978p; GTP binding; GTPase activity. It is involved in the biological process described with: tRNA methylation; tRNA wobble uridine modification; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | 0.806 |
| CG18528 | CG4610 | FBpp0084012 | FBpp0071745 | RE57978p; GTP binding; GTPase activity. It is involved in the biological process described with: tRNA methylation; tRNA wobble uridine modification; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | GH24245p; Flavin adenine dinucleotide binding. It is involved in the biological process described with: mitochondrial tRNA wobble uridine modification; tRNA methylation; tRNA wobble uridine modification. | 0.998 |
| CG3021 | CG11109 | FBpp0070168 | FBpp0078203 | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | FI01826p; Methyltransferase activity; RNA binding. It is involved in the biological process described with: RNA methylation; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.807 |
| CG3021 | CG1434 | FBpp0070168 | FBpp0308524 | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | GH10289p; Flavin adenine dinucleotide binding; tRNA dihydrouridine synthase activity. It is involved in the biological process described with: tRNA dihydrouridine synthesis; oxidation-reduction process. | 0.817 |
| CG3021 | CG18528 | FBpp0070168 | FBpp0084012 | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | RE57978p; GTP binding; GTPase activity. It is involved in the biological process described with: tRNA methylation; tRNA wobble uridine modification; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.806 |
| CG3021 | CG32281 | FBpp0070168 | FBpp0072898 | Mitochondrial tRNA-specific 2-thiouridylase 1; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. Belongs to the MnmA/TRMU family. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family. | 0.877 |