STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
su(w[a])Protein suppressor of white apricot; Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulates its own expression at the level of RNA processing. (963 aa)    
Predicted Functional Partners:
CG32590
BLOC-1-related complex subunit 8 homolog; May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor; Belongs to the BORCS8 family.
      
 0.839
CG5707
MIP21537p; Hydrolase activity.
      
 0.790
CG9500
Fibrinogen C-terminal domain-containing protein.
      
 0.669
Cpr50Ca
Cuticular protein 50Ca; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.668
tapas
Tapas, isoform B; It is involved in the biological process described with: negative regulation of transposition; piRNA biosynthetic process.
      
 0.628
Nop60B
H/ACA ribonucleoprotein complex subunit 4; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. Required for maintenance of the germline stem cell lineage during spermatogenesis; Belongs to the pseudouridine synthase TruB family.
      
 0.602
Sh
Potassium voltage-gated channel protein Shaker; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Forms rapidly inactivating tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient and may contribute to A- type currents. Plays a role in the regulation of sleep need or efficiency ; Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) s [...]
      
 0.529
Cyp28d1
Probable cytochrome P450 28d1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
   
  
 0.501
mri
Mrityu, isoform A; Mrityu (mri) encodes a BTB/POZ domain containing protein. Its expression is regulated by the product of klu during retinal apoptosis. mri protein is phosphorylated upon egg activation, and is required for early embryo development and for the normal sensory perception of touch.
      
 0.491
CG10140
Uncharacterized protein; Chitin binding. It is involved in the biological process described with: chitin metabolic process.
      
 0.491
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (32%) [HD]