Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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su(w[a])Protein suppressor of white apricot; Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulates its own expression at the level of RNA processing. (963 aa)    
Predicted Functional Partners:
Bug22
Cilia- and flagella-associated protein 20; Basal body up regulated gene 22 (Bug22) encodes a ciliary protein involved in cilium organization and assembly. It contributes to multiple processes during spermatogenesis including tubulin polyglycylation, axoneme assembly, sperm individualization and motility. It also contributes to locomotion, dendrite morphogenesis and neuron and muscle development; Belongs to the CFAP20 family.
    
   0.836
CG1622
FI05227p; It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
   0.834
CG5707
MIP21537p; Hydrolase activity.
      
 0.824
Hexim
Hexamethylene bisacetamide inducible (Hexim) encodes an RNA binding protein. When associated with snRNA:7SK, it recruits and inhibits the positive transcription elongation factor encoded by Cdk9. Regulated release and re-sequestration of the product of Cdk9 by the snRNA:7SK snRNP plays an essential role in RNA polymerase II elongation control.
    
   0.821
rb
Ruby (rb) encodes the beta3-adaptin subunit of the Adaptor protein-3 (AP-3) complex involved in biogenesis of lysosome-related organelles. It is required for regulation of lipid storage, eye pigment biogenesis and the processing of the receptor encoded by N.
    
   0.805
CG9776
Zinc finger matrin-type protein CG9776; It is involved in the biological process described with: positive regulation of transcription, DNA-templated; negative regulation of transcription, DNA-templated.
   
   0.778
Cpr50Ca
Cuticular protein 50Ca; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.744
CG9500
Fibrinogen C-terminal domain-containing protein.
      
 0.743
w
White (w) encodes a member of the ABCG2 class of transporters, transporting molecules such as cyclic GMP, biogenic amines and pigments including drosopterins and ommochromes. Mutation of w results in viable flies with white eyes. A shortened version of the gene (mini-w) has been widely used in transformation constructs as a selectable marker.
    
   0.701
tapas
Tapas, isoform B; It is involved in the biological process described with: negative regulation of transposition; piRNA biosynthetic process.
      
 0.614
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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