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su(w[a]) protein (fruit fly) - STRING interaction network
"su(w[a])" - RNA binding in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
su(w[a])RNA binding; Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulate its own expression at the level of RNA processing (963 aa)    
Predicted Functional Partners:
su(s)
RNA binding; Affects the transcript levels of those alleles that it suppresses. May be involved in influencing complex assembly on cryptic 5’-splice sites or nuclear RNA export; binds RNA preferentially at a sequence that resembles a cryptic 5’-splice site (in vitro) (1325 aa)
     
   
  0.754
SRm160
SRm160 (954 aa)
     
 
  0.636
scaf6
mRNA binding (960 aa)
     
   
  0.613
fus
Fusilli; mRNA splicing factor that regulates alternative splicing od specific genes. Has a maternal role in embryonic dorsal-ventral patterning; such role is probably indirect and due to its function as mRNA splicing factor regulator (967 aa)
     
   
  0.538
CG16941
RNA binding (784 aa)
     
   
  0.515
noi
Noisette; Probable subunit of a splicing factor complex required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (By similarity). Involved in male fertility (503 aa)
           
  0.505
su(f)
Suppressor of forked; Essential protein, may play a role in mRNA production or stability (765 aa)
     
   
  0.486
CG10754
Zinc ion binding; nucleic acid binding (264 aa)
           
  0.481
Arpc1
Suppressor of profilin 2 (377 aa)
           
  0.474
tra2
Transformer 2; Required for female sex determination in somatic cells and for spermatogenesis in male germ cells. Positive regulator of female-specific splicing and/or polyadenylation of doublesex (dsx) pre-mRNA. Splicing requires an enhancer complex, dsxRE (dsx repeat element- which contains six copies of a 13-nucleotide repeat and a purine-rich enhancer (PRE)). DsxRE is formed through cooperative interactions between tra, tra2 and the sr proteins, and these interactions require both the repeat sequences and PRE. PRE is required for specific binding of tra2 to the dsxRE. Protein-RNA a [...] (264 aa)
     
   
  0.448
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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