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STRINGSTRING
CG11638 protein (fruit fly) - STRING interaction network
"CG11638" - RE52086p in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11638RE52086p; Calcium ion binding (387 aa)    
Predicted Functional Partners:
CG2258
CG2258, isoform A; Myosin binding (801 aa)
           
  0.857
KCNQ
KCNQ potassium channel, isoform F; Delayed rectifier potassium channel activity; voltage-gated potassium channel activity; voltage-gated cation channel activity. It is involved in the biological process described with- embryonic development via the syncytial blastoderm; transmembrane transport; potassium ion transport; regulation of heart rate; cardiac muscle contraction (993 aa)
       
 
  0.686
sick
Sickie (Sick) is a cytoskeletal protein that positively regulates F-actin-mediated axonal growth by relaying the non-canonical RacGTPase-Slingshot-Cofilin pathway. Sick also mediates immune deficiency signaling pathway, which activates Rel (2707 aa)
           
  0.590
CASK
Peripheral plasma membrane protein CASK; CASK is a member of the MAGUK family of scaffolding proteins. In epithelial tissues, CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity; In the N-terminal section; belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily (916 aa)
       
 
  0.560
CG5220
Putative tRNA (cytidine(32)/guanosine(34)-2’-O)-methyltransferase 1; Methylates the 2’-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs (302 aa)
           
  0.556
pall
Pallbearer (Pall) is an F-Box protein. In response to apoptosis, Pall translocates from the nucleus to the cytoplasm of macrophages to promote apoptotic cell clearance by degrading RpS6, and promote actin remodeling through activation of Rac2 (314 aa)
           
  0.543
CG42672
annotation not available (1650 aa)
     
 
  0.527
para
Sodium channel protein para; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient; Belongs to the sodium channel (TC 1.A.1.10) family. Para subfamily (2143 aa)
     
 
  0.509
CycK
Protein kinase binding; cyclin-dependent protein serine/threonine kinase regulator activity. It is involved in the biological process described with- regulation of transcription, DNA-templated; neurogenesis; regulation of cyclin-dependent protein serine/threonine kinase activity (400 aa)
           
  0.500
P5cr-2
Pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with- oxidation-reduction process; proline biosynthetic process (273 aa)
       
 
  0.499
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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