node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Burs | CG11638 | FBpp0083529 | FBpp0070176 | Bursicon (Burs) encodes a cystine knot protein that dimerizes with the product of Pburs to form the bursicon neurohormone. Bursicon neurohormone is released after adult emergence and acts on the receptor encoded by rk for tanning and hardening of the cuticle and expansion of the wings. | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 0.599 |
CASK | CG11638 | FBpp0303394 | FBpp0070176 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 0.678 |
CASK | Lrrk | FBpp0303394 | FBpp0306703 | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. | 0.893 |
CG11638 | Burs | FBpp0070176 | FBpp0083529 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | Bursicon (Burs) encodes a cystine knot protein that dimerizes with the product of Pburs to form the bursicon neurohormone. Bursicon neurohormone is released after adult emergence and acts on the receptor encoded by rk for tanning and hardening of the cuticle and expansion of the wings. | 0.599 |
CG11638 | CASK | FBpp0070176 | FBpp0303394 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity. | 0.678 |
CG11638 | CG15651 | FBpp0070176 | FBpp0071482 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | FI03527p; It is involved in the biological process described with: protein O-linked mannosylation. | 0.599 |
CG11638 | CG2258 | FBpp0070176 | FBpp0309126 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | LD35927p; Myosin binding. | 0.836 |
CG11638 | Fkbp12 | FBpp0070176 | FBpp0085703 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 12 kDa FK506-binding protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Binds to ligand-free TGF beta type I receptor, from which it is released upon a ligand-induced, type II receptor mediated phosphorylation of the type I receptor. Binding is inhibitory to the signaling pathways of the TGF beta family ligands. | 0.521 |
CG11638 | KCNQ | FBpp0070176 | FBpp0290659 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | KCNQ potassium channel, isoform F; KCNQ potassium channel (KCNQ) encodes a voltage-gated channel involved in cardiac muscle contraction; Belongs to the potassium channel family. | 0.804 |
CG11638 | Lrrk | FBpp0070176 | FBpp0306703 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. | 0.592 |
CG11638 | Oatp26F | FBpp0070176 | FBpp0078956 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | Solute carrier organic anion transporter family member; Transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; active transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; sodium-independent organic anion transport; organic substance transport. | 0.543 |
CG11638 | pall | FBpp0070176 | FBpp0076199 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | Pallbearer (pall) encodes an F-Box protein. In response to apoptosis, it translocates from the nucleus to the cytoplasm of macrophages to promote apoptotic cell clearance by degrading the product of RpS6, and promote actin remodeling through activation of the product of Rac2. | 0.650 |
CG11638 | sick | FBpp0070176 | FBpp0302887 | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | Sickie (sick) encodes a cytoskeletal protein that positively regulates F-actin-mediated axonal growth by relaying the non-canonical RacGTPase-Slingshot-Cofilin pathway. It also mediates immune deficiency signaling pathway, which activates the product of Rel; Belongs to the Nav/unc-53 family. | 0.647 |
CG15651 | CG11638 | FBpp0071482 | FBpp0070176 | FI03527p; It is involved in the biological process described with: protein O-linked mannosylation. | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 0.599 |
CG15651 | Lrrk | FBpp0071482 | FBpp0306703 | FI03527p; It is involved in the biological process described with: protein O-linked mannosylation. | Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. | 0.419 |
CG2258 | CG11638 | FBpp0309126 | FBpp0070176 | LD35927p; Myosin binding. | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 0.836 |
CG2258 | Oatp26F | FBpp0309126 | FBpp0078956 | LD35927p; Myosin binding. | Solute carrier organic anion transporter family member; Transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; active transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; sodium-independent organic anion transport; organic substance transport. | 0.400 |
CG2258 | pall | FBpp0309126 | FBpp0076199 | LD35927p; Myosin binding. | Pallbearer (pall) encodes an F-Box protein. In response to apoptosis, it translocates from the nucleus to the cytoplasm of macrophages to promote apoptotic cell clearance by degrading the product of RpS6, and promote actin remodeling through activation of the product of Rac2. | 0.507 |
CG2258 | sick | FBpp0309126 | FBpp0302887 | LD35927p; Myosin binding. | Sickie (sick) encodes a cytoskeletal protein that positively regulates F-actin-mediated axonal growth by relaying the non-canonical RacGTPase-Slingshot-Cofilin pathway. It also mediates immune deficiency signaling pathway, which activates the product of Rel; Belongs to the Nav/unc-53 family. | 0.612 |
Fkbp12 | CG11638 | FBpp0085703 | FBpp0070176 | 12 kDa FK506-binding protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Binds to ligand-free TGF beta type I receptor, from which it is released upon a ligand-induced, type II receptor mediated phosphorylation of the type I receptor. Binding is inhibitory to the signaling pathways of the TGF beta family ligands. | RE52086p; Enzyme regulator activity; calcium ion binding. It is involved in the biological process described with: calcium-mediated signaling; microtubule cytoskeleton organization. | 0.521 |