STRINGSTRING
CG11638 protein (fruit fly) - STRING interaction network
"CG11638" - Calcium ion binding in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11638Calcium ion binding (387 aa)    
Predicted Functional Partners:
Nos
Nitric oxide synthase; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3-isoform 6) are able to form intracellular complexes with the full length protein and serve as dominant negative inhibitors of the enzyme activity (1349 aa)
     
 
  0.943
NaCP60E
Na channel protein 60E; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Plays a role in processing of olfactory information during the olfactory avoidance response (2896 aa)
     
 
  0.801
na
Narrow abdomen (2232 aa)
     
 
  0.802
Ca-alpha1D
Voltage-gated calcium channel activity; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Encodes a dihydropyridine- and diltiazem-sensitive current in larval body wall muscle. Vital for embryonic development (2552 aa)
     
 
  0.793
Mhcl
Myosin heavy chain-like (2194 aa)
     
 
  0.781
para
Paralytic; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (2145 aa)
       
 
  0.772
Pp2B-14D
Protein binding; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (570 aa)
     
 
  0.766
CanA-14F
Calcineurin A at 14F; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (584 aa)
     
 
  0.766
CanA1
Calcineurin A1; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (622 aa)
     
 
  0.766
Unc-89
Unc-89 (4218 aa)
     
  0.756
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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