STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsp2ATetraspanin-2A; Required for assembly of smooth septate junctions (sSJs), together with Ssk and mesh. Important for barrier function of the midgut epithelium; Belongs to the tetraspanin (TM4SF) family. (244 aa)    
Predicted Functional Partners:
Ssk
Protein snakeskin; Required for assembly of smooth septate junctions (sSJs), together with mesh and Tsp2A. May be important for barrier function of the midgut epithelium.
   
 
 0.992
Tsp29Fb
Tetraspanin.
   
  
 0.787
CG9568
LP01634p.
   
    0.750
Decay
Death executioner caspase related to Apopain/Yama (Decay) encodes one of the seven members of the caspase family of cysteine proteases. It has substrate specificity similar to the effector caspases encoded by Drice and Dcp-1; Belongs to the peptidase C14A family.
   
    0.750
Tsp42Ec
Tetraspanin.
   
  
 0.748
CG13321
RE03883p.
   
    0.744
CG33127
IP10114p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
  
 0.721
CG4301
ATPase-coupled intramembrane lipid transporter activity; ATP binding; magnesium ion binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
  
 0.695
CG3868
Uncharacterized protein.
   
  
 0.691
CG5096
RE59088p.
   
  
 0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.