STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Coa8COA8 family protein CG14806, mitochondrial; May be required for cytochrome c complex (COX) assembly and function, COX being the terminal component of the mitochondrial respiratory chain; Belongs to the COA8 family. (176 aa)    
Predicted Functional Partners:
CG6479
FI08815p.
      
 0.893
Ccdc58
Coiled-coil domain-containing 58, isoform A.
   
  
 0.857
Uck
Uridine-cytidine kinase; (Microbial infection) Required for optimal replication of E.chaffeensis in the immune tissues, hemocytes, and fat body. Belongs to the uridine kinase family.
      
 0.826
CG31648
RE57459p; Copper ion binding. It is involved in the biological process described with: aerobic respiration; respiratory chain complex IV assembly.
   
  
 0.511
Nup37
Nucleoporin Nup37; As part of the nuclear pore complex (NPC), has a role in its assembly and function.
   
  
 0.494
CTPsyn
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity). Isoform 1 is required for cytoophidium assembly in female germline cells.
      
 0.493
CG8097
RE16047p; arginine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: arginyl-tRNA aminoacylation.
      
 0.491
Echs1
Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family.
   
  
 0.450
CG11695
GH18834p; Transcription regulatory region sequence-specific DNA binding; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
  
 0.435
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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