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Pgd protein (fruit fly) - STRING interaction network
"Pgd" - Phosphogluconate dehydrogenase in Drosophila melanogaster
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PgdPhosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (481 aa)    
Predicted Functional Partners:
Zw
Zwischenferment; Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity) (524 aa)
 
 
  0.997
CG17333
6-phosphogluconolactonase activity; Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate (243 aa)
   
 
  0.973
Tal
Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (331 aa)
   
 
  0.948
CG30499
Ribulose-phosphate 3-epimerase (221 aa)
   
  0.947
Rpi
Ribose-5-phosphate isomerase (241 aa)
   
 
  0.943
Pgi
Phosphoglucose isomerase (558 aa)
   
   
  0.935
Pgm
Phosphogluconate mutase; This enzyme participates in both the breakdown and synthesis of glucose (560 aa)
   
   
  0.914
Trxr-1
Thioredoxin reductase-1; Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms (596 aa)
   
 
  0.906
Mdh2
Malate dehydrogenase 2 (336 aa)
   
 
  0.840
CG8036
Transketolase activity (626 aa)
   
 
  0.838
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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