node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG17333 | CG5103 | FBpp0073235 | FBpp0074898 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | 0.783 |
CG17333 | CG7140 | FBpp0073235 | FBpp0113038 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. | 0.988 |
CG17333 | CG8036 | FBpp0073235 | FBpp0081370 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing. | 0.774 |
CG17333 | Idh | FBpp0073235 | FBpp0305272 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Isocitrate dehydrogenase (Idh) encodes a cytosolic enzyme that catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate, with the concomitant reduction of NADP[+] to NADPH. It functions, along with Men, Zw, and Pgd, in a small network of NADP reducing enzymes. | 0.512 |
CG17333 | Mpi | FBpp0073235 | FBpp0081609 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Zinc ion binding; mannose-6-phosphate isomerase activity. It is involved in the biological process described with: GDP-mannose biosynthetic process; carbohydrate metabolic process. | 0.535 |
CG17333 | Pgd | FBpp0073235 | FBpp0070368 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 6-phosphogluconate dehydrogenase, decarboxylating; Phosphogluconate dehydrogenase (Pgd) encodes a cytosolic enzyme that catalyzes the oxidation of 6-phosphogluconate to ribulose 5-phosphate, with the concomitant reduction of NADP[+] to NADPH. The products of Pgd and Zw are the two NADP[+] reducing enzymes in the pentose phosphate pathway. | 0.985 |
CG17333 | Rpe | FBpp0073235 | FBpp0088028 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Metal ion binding; ribulose-phosphate 3-epimerase activity. It is involved in the biological process described with: cellular carbohydrate metabolic process; pentose catabolic process; pentose-phosphate shunt, non-oxidative branch. | 0.697 |
CG17333 | Rpi | FBpp0073235 | FBpp0296955 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Ribose-5-phosphate isomerase activity. It is involved in the biological process described with: age-dependent response to reactive oxygen species; D-ribose metabolic process; pentose-phosphate shunt, non-oxidative branch. | 0.720 |
CG17333 | Taldo | FBpp0073235 | FBpp0072050 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.928 |
CG17333 | Zw | FBpp0073235 | FBpp0074517 | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | Glucose-6-phosphate 1-dehydrogenase; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes. | 0.989 |
CG5103 | CG17333 | FBpp0074898 | FBpp0073235 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Probable 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.783 |
CG5103 | CG7140 | FBpp0074898 | FBpp0113038 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. | 0.786 |
CG5103 | CG8036 | FBpp0074898 | FBpp0081370 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing. | 0.901 |
CG5103 | Idh | FBpp0074898 | FBpp0305272 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Isocitrate dehydrogenase (Idh) encodes a cytosolic enzyme that catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate, with the concomitant reduction of NADP[+] to NADPH. It functions, along with Men, Zw, and Pgd, in a small network of NADP reducing enzymes. | 0.651 |
CG5103 | Mpi | FBpp0074898 | FBpp0081609 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Zinc ion binding; mannose-6-phosphate isomerase activity. It is involved in the biological process described with: GDP-mannose biosynthetic process; carbohydrate metabolic process. | 0.589 |
CG5103 | Pgd | FBpp0074898 | FBpp0070368 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | 6-phosphogluconate dehydrogenase, decarboxylating; Phosphogluconate dehydrogenase (Pgd) encodes a cytosolic enzyme that catalyzes the oxidation of 6-phosphogluconate to ribulose 5-phosphate, with the concomitant reduction of NADP[+] to NADPH. The products of Pgd and Zw are the two NADP[+] reducing enzymes in the pentose phosphate pathway. | 0.946 |
CG5103 | Rpe | FBpp0074898 | FBpp0088028 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Metal ion binding; ribulose-phosphate 3-epimerase activity. It is involved in the biological process described with: cellular carbohydrate metabolic process; pentose catabolic process; pentose-phosphate shunt, non-oxidative branch. | 0.984 |
CG5103 | Rpi | FBpp0074898 | FBpp0296955 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Ribose-5-phosphate isomerase activity. It is involved in the biological process described with: age-dependent response to reactive oxygen species; D-ribose metabolic process; pentose-phosphate shunt, non-oxidative branch. | 0.962 |
CG5103 | Taldo | FBpp0074898 | FBpp0072050 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.999 |
CG5103 | Zw | FBpp0074898 | FBpp0074517 | FI06132p; Transketolase activity; thiamine pyrophosphate binding. | Glucose-6-phosphate 1-dehydrogenase; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes. | 0.822 |