STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3630EG:152A3.3 protein; Actin binding. It is involved in the biological process described with: positive regulation of Rho protein signal transduction; positive regulation of DNA-binding transcription factor activity; positive regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated. (371 aa)    
Predicted Functional Partners:
CG6752
AT01875p; Ubiquitin protein ligase activity; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process.
      
 0.791
CG11737
RE12402p; It is involved in the biological process described with: peroxisome organization.
      
 0.674
Nulp1
Nuclear localized protein 1, isoform A; DNA-binding transcription factor activity. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II; positive regulation of canonical Wnt signaling pathway.
      
 0.672
CG34408
Uncharacterized protein, isoform H; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; activation of GTPase activity.
      
 0.669
CG5455
GH15286p; It is involved in the biological process described with: extracellular matrix organization.
      
 0.609
Apt1
Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation.
   
  
 0.608
Ythdf
YTH domain-containing family protein; Specifically recognizes and binds N6-methyladenosine (m6A)- containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA processing and stability.
      
 0.599
Tmem131
Transmembrane protein 131 homolog.
      
 0.539
OstDelta
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
      
 0.533
aralar1
Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane.
   
  
 0.511
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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