• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
temp protein (fruit fly) - STRING interaction network
"temp" - Tempura, isoform A in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tempTempura, isoform A; Rab geranylgeranyltransferase activity. It is involved in the biological process described with- protein geranylgeranylation; sensory organ development (398 aa)    
Predicted Functional Partners:
betaggt-II
Beta subunit of type II geranylgeranyl transferase; CAAX-protein geranylgeranyltransferase activity; Rab geranylgeranyltransferase activity. It is involved in the biological process described with- protein geranylgeranylation (347 aa)
     
  0.996
Rep
Rab proteins geranylgeranyltransferase component A; Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity) (511 aa)
     
  0.993
CG12007
LD31216p; Rab geranylgeranyltransferase activity. It is involved in the biological process described with- regulation of cell shape; protein geranylgeranylation; neurogenesis; cell adhesion (515 aa)
         
0.919
Rab1
FI01544p; GTPase activity; GTP binding (205 aa)
       
 
  0.808
CG17565
LD36454p; Rab geranylgeranyltransferase activity. It is involved in the biological process described with- regulation of cell proliferation; protein farnesylation (419 aa)
     
 
  0.787
betaggt-I
Beta subunit of type I geranylgeranyl transferase, isoform A; CAAX-protein geranylgeranyltransferase activity; protein geranylgeranyltransferase activity. It is involved in the biological process described with- positive regulation of Ras protein signal transduction; positive regulation of ERK1 and ERK2 cascade; embryonic heart tube development; neurogenesis; Ras protein signal transduction (395 aa)
     
 
  0.769
Gdi
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP (443 aa)
     
 
  0.698
Rab11
Rab11, isoform A; Rab11 is a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions (214 aa)
       
 
  0.614
ste14
Protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. It is involved in the biological process described with- C-terminal protein methylation (299 aa)
     
   
  0.546
cm
Mu3 subunit of clathrin-associated protein complex AP-3; Protein transporter activity; Belongs to the adaptor complexes medium subunit family (415 aa)
     
   
  0.488
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
Server load: low (9%) [HD]