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Nmd3 protein (fruit fly) - STRING interaction network
"Nmd3" - 60S ribosomal export protein NMD3 in Drosophila melanogaster
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
Nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit (521 aa)    
Predicted Functional Partners:
Ns3
Large subunit GTPase 1 homolog; GTPase required for the nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of Nmd3 from the 60S ribosomal subunit after export into the cytoplasm. Regulator of body size; acts in serotonergic neurons to regulate insulin signaling and thus exerts global growth control (606 aa)
     
 
  0.997
CG10576
Uncharacterized protein, isoform A; Aminopeptidase activity (391 aa)
     
 
  0.992
RpLP0-like
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes (256 aa)
     
 
  0.990
bys
Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (436 aa)
     
   
  0.989
Non1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle. May be involved in both centrosome- dependent and centrosome-independent spindle assembly programs (652 aa)
   
 
  0.988
CG7686
annotation not available (493 aa)
     
   
  0.988
CG2691
RRP12-like protein; It is involved in the biological process described with- neuron projection morphogenesis (1384 aa)
     
   
  0.988
RpL24-like
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity) (191 aa)
     
 
  0.987
eIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis (245 aa)
     
 
  0.985
Ns1
Guanine nucleotide-binding protein-like 3 homolog; May play a role in regulating cellular proliferation; Belongs to the TRAFAC class YlqF/YawG GTPase family (581 aa)
     
 
  0.985
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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