STRINGSTRING
Nmd3 protein (fruit fly) - STRING interaction network
"Nmd3" - mRNA binding in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nmd3mRNA binding (521 aa)    
Predicted Functional Partners:
CG8801
GTP binding; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle (PubMed-24255106). May be involved in both centrosome- dependent and centrosome-independent spindle assembly programs (PubMed-24255106) (652 aa)
     
 
  0.991
Ns3
GTP binding; GTPase required for the nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of Nmd3 from the 60S ribosomal subunit after export into the cytoplasm. Regulator of body size; acts in serotonergic neurons to regulate insulin signaling and thus exerts global growth control (606 aa)
     
 
  0.990
Ns1
GTP binding; May play a role in regulating cellular proliferation (581 aa)
     
 
  0.986
CG10576
Aminopeptidase activity (391 aa)
     
 
  0.985
Ns4
GTP binding (575 aa)
     
 
  0.979
CG5033
Ribonucleoprotein complex binding; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (784 aa)
     
   
  0.977
CG4364
Pescadillo homolog ; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (627 aa)
     
   
  0.975
CG7993
Novel nucleolar protein 3; Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome- independent spindle assembly programs (320 aa)
     
   
  0.975
CG7006
RNA binding; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly (180 aa)
     
   
  0.973
Nle
Notchless; Plays a role in regulating Notch activity (488 aa)
     
   
  0.972
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
Server load: low (14%) [HD]