STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG14422LP21102p. (294 aa)    
Predicted Functional Partners:
CG3857
Protein SMG9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
      
 0.661
TfIIFbeta
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity (By similarity).
      
 0.602
CG6293
MIP03523p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.601
CG14417
EG:BACR43E12.6 protein.
   
    0.566
CG7839
IP14658p; It is involved in the biological process described with: ribosome biogenesis.
      
 0.493
CG32793
Uncharacterized protein.
   
    0.454
CG14424
EG:100G7.5 protein.
   
    0.444
CG3598
Uncharacterized protein.
   
    0.416
CG17959
Uncharacterized protein.
   
    0.412
CG9287
COesterase domain-containing protein.
   
    0.406
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.