STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10802LD13611p; Ser-tRNA(Ala) hydrolase activity; ATP binding; nucleic acid binding; alanine-tRNA ligase activity. It is involved in the biological process described with: alanyl-tRNA aminoacylation; regulation of translational fidelity. (436 aa)    
Predicted Functional Partners:
GluProRS
Bifunctional glutamate/proline--tRNA ligase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
     
 0.682
TyrRS
tRNA binding; tyrosine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: tyrosyl-tRNA aminoacylation.
   
  
 0.662
mtTFB1
Dimethyladenosine transferase 1, mitochondrial; Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. In contrast to mtTFB2, it does not have a critical role in either transcription or regulation of the copy number of mitochondrial DNA.
      
 0.610
GluRS-m
Glutamyl-tRNA synthetase, mitochondrial; glutamate-tRNA ligase activity; tRNA binding; ATP binding; zinc ion binding. It is involved in the biological process described with: glutamyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.609
LysRS
Lysine--tRNA ligase; tRNA binding; ATP binding; lysine-tRNA ligase activity. It is involved in the biological process described with: lysyl-tRNA aminoacylation.
   
  
 0.607
Ip259
Intronic protein 259, isoform A; It is involved in the biological process described with: maturation of LSU-rRNA; maturation of 5.8S rRNA.
      
 0.576
CG1785
Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis, being required for integration of the 5S RNP into the ribosomal large subunit. Belongs to the NOP53 family.
   
  
 0.571
IleRS
Isoleucyl-tRNA synthetase, isoform A; isoleucine-tRNA ligase activity; tRNA binding; aminoacyl-tRNA editing activity; ATP binding. It is involved in the biological process described with: isoleucyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.569
Non1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
  
 0.569
CG17486
Asparagine synthetase domain-containing protein CG17486; Asparagine synthase (glutamine-hydrolyzing) activity. It is involved in the biological process described with: asparagine biosynthetic process.
     
 0.504
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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