STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sas10Something about silencing 10 (Sas10) encodes a protein belonging to the SAS10 family. It might be a substrate of the RNA deaminase encoded by Adar, which shows an adenosine to inosine (A-to-I) deaminase activity in pre-mRNA transcripts. The noncoding strand of the adjacent gene, Rnp4F, reads through to form a duplex with Sas10 transcripts at their 3'-end to target both transcripts for promiscuous A-to-I editing and degradation. (428 aa)    
Predicted Functional Partners:
CG2260
LD41718p; It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 0.997
CG1789
Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.
   
 0.996
dbe
KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Binds to RNA. Required for female germline development, cell viability during eye development and for survival of dividing cells and epithelial cells during early wing disk development.
   
 0.996
CG12301
LD31322p; It is involved in the biological process described with: rRNA processing; mushroom body development.
   
 0.995
CG11920
FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing.
   
 0.995
CG7275
LD28275p; It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 0.993
l(2)34Fd
Lethal (2) 34Fd; It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 0.993
l(3)07882
Nucleolar protein 14 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
   
 0.993
wcd
U3 small nucleolar RNA-associated protein 18 homolog; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA. Regulation of cell size by ribosome synthesis is an important parameter for stem cell maintenance and function; Belongs to the WD repeat UTP18 family.
   
 0.992
Bka
RE14259p.
   
 0.991
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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