Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...]

Uncharacterized protein CG16817; prostaglandin-E synthase activity; Hsp90 protein binding; chaperone binding. It is involved in the biological process described with: protein folding; positive regulation of small RNA loading onto RISC; chaperone-mediated protein complex assembly; Belongs to the p23/wos2 family.

Superoxide dismutase 2 (Mn) (Sod2) encodes an enzyme that detoxifies superoxide radicals in mitochondria. The loss of Sod2 generates endogenous oxidative stress that results in reduced activity of critical mitochondrial enzymes, hypersensitivity to oxidative stress and neonatal lethality. A muscle restricted p38Kinase-Mef2-Sod2 signaling module influences life span and stress.

Mitochondrial ribosomal protein L3; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.

39S ribosomal protein L13, mitochondrial; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: negative regulation of translation; mitochondrial translation; translation; Belongs to the universal ribosomal protein uL13 family.

Mitochondrial ribosomal protein L15; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.

Mitochondrial ribosomal protein L21, isoform A; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.

Mitochondrial ribosome-associated GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity (By similarity). Displays mitochondrial GTPase activity (By similarity). Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

39S ribosomal protein L11, mitochondrial; Structural constituent of ribosome; large ribosomal subunit rRNA binding; rRNA binding. It is involved in the biological process described with: mitochondrial translation; translation; ribosomal large subunit assembly; Belongs to the universal ribosomal protein uL11 family.