STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xitProbable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). Functions in developmental processes such as germband extension, the apical constriction of mesoderm precursor cells and ventral furrow formation in early embryogenesis prior to gastrulation. Involved in the glycosylation and intracellular distribution of shg ( [...] (511 aa)    
Predicted Functional Partners:
gny
Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. Involved in cuticle differentiation.
  
0.999
Alg10
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG10 glucosyltransferase family.
  
 0.934
CG32650
Uncharacterized protein.
      
 0.912
CG11920
FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing.
 
 
    0.867
Alg3
Lethal(2)neighbour of tid protein; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation.
   
 
 0.745
Alg7
GH19029p; phospho-N-acetylmuramoyl-pentapeptide-transferase activity; UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; dolichyl diphosphate biosynthetic process.
   
  
 0.699
mkg-p
Monkey king protein, isoform A; RNA uridylyltransferase activity; nucleotidyltransferase activity. It is involved in the biological process described with: mRNA processing; pre-miRNA processing; RNA 3' uridylation.
      
 0.668
jim
Jim, isoform F; Jim (jim) encodes a zinc finger C2H2 transcription factor involved in dendrite morphogenesis and regulation of chromatin silencing.
      
 0.666
IRSp53
Insulin receptor substrate 53 kDa (IRSp53) encodes a protein required for filopodia formation during the adhesion and fusion of myoblasts.
   
 
 0.663
GCS2alpha
Glucan 1,3-alpha-glucosidase activity; carbohydrate binding. It is involved in the biological process described with: carbohydrate metabolic process; Belongs to the glycosyl hydrolase 31 family.
   
 
 0.662
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: medium (42%) [HD]