node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10591 | Inx2 | FBpp0076834 | FBpp0304593 | Uncharacterized protein. | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | 0.497 |
CG3655 | Inx2 | FBpp0303757 | FBpp0304593 | Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family. | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | 0.504 |
CG3655 | MEP-1 | FBpp0303757 | FBpp0288779 | Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family. | MEP-1, isoform A; MEP-1 (MEP-1) encodes a zinc finger protein that associates with the ATP-dependent nucleosome remodeler encoded by Mi-2. It cooperates with the product of Mi-2 in the repression of cell type-specific genes. | 0.461 |
CG3655 | dy | FBpp0303757 | FBpp0073449 | Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family. | LP20007p; Dusky (dy) encodes a membrane-anchored protein of the zona pellucida domain protein familiy. Along with the homologous gene m, it regulates epidermal cell size/shape changes during wing morphogenesis. It also functions to remodel epidermal cell shape during embryonic and later developmental stages, through interactions with the extracellular matrix. | 0.494 |
CG3655 | ogre | FBpp0303757 | FBpp0306903 | Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family. | Innexin inx1; Optic ganglion reduced (ogre) encodes one of the innexin subunits spanning the membrane 4 times. Together with the products of Inx2 and Inx3, it forms homo or hetero oligomers forming gap junctions, which allow the transfer of small solute between cells. | 0.443 |
CG3655 | pio | FBpp0303757 | FBpp0290717 | Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family. | Piopio, isoform B; Piopio (pio) encodes a zona pellucida (ZP) domain protein that mediates the adhesion of the apical epithelial surface and the overlying apical extracellular matrix. | 0.467 |
CG4942 | Inx2 | FBpp0076251 | FBpp0304593 | LD38503p; Membrane insertase activity. It is involved in the biological process described with: protein insertion into mitochondrial inner membrane from matrix; protein insertion into membrane; mitochondrial cytochrome c oxidase assembly. | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | 0.535 |
Inx2 | CG10591 | FBpp0304593 | FBpp0076834 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | Uncharacterized protein. | 0.497 |
Inx2 | CG3655 | FBpp0304593 | FBpp0303757 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family. | 0.504 |
Inx2 | CG4942 | FBpp0304593 | FBpp0076251 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | LD38503p; Membrane insertase activity. It is involved in the biological process described with: protein insertion into mitochondrial inner membrane from matrix; protein insertion into membrane; mitochondrial cytochrome c oxidase assembly. | 0.535 |
Inx2 | Inx3 | FBpp0304593 | FBpp0303338 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | Innexin 3 (Inx3) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the product of Inx2. Loss of Inx3 leads to the destabilization of the products of ogre, Inx2 and shg at the plasma membrane, suggesting that these four proteins form a complex. | 0.742 |
Inx2 | MEP-1 | FBpp0304593 | FBpp0288779 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | MEP-1, isoform A; MEP-1 (MEP-1) encodes a zinc finger protein that associates with the ATP-dependent nucleosome remodeler encoded by Mi-2. It cooperates with the product of Mi-2 in the repression of cell type-specific genes. | 0.507 |
Inx2 | dy | FBpp0304593 | FBpp0073449 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | LP20007p; Dusky (dy) encodes a membrane-anchored protein of the zona pellucida domain protein familiy. Along with the homologous gene m, it regulates epidermal cell size/shape changes during wing morphogenesis. It also functions to remodel epidermal cell shape during embryonic and later developmental stages, through interactions with the extracellular matrix. | 0.522 |
Inx2 | ogre | FBpp0304593 | FBpp0306903 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | Innexin inx1; Optic ganglion reduced (ogre) encodes one of the innexin subunits spanning the membrane 4 times. Together with the products of Inx2 and Inx3, it forms homo or hetero oligomers forming gap junctions, which allow the transfer of small solute between cells. | 0.607 |
Inx2 | pio | FBpp0304593 | FBpp0290717 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | Piopio, isoform B; Piopio (pio) encodes a zona pellucida (ZP) domain protein that mediates the adhesion of the apical epithelial surface and the overlying apical extracellular matrix. | 0.515 |
Inx2 | shg | FBpp0304593 | FBpp0071475 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | DE-cadherin; Cadherins are calcium-dependent cell adhesion proteins. In connecting cells they preferentially interact with themselves in a homophilic manner; cadherins may thus contribute to the sorting of heterogeneous cell types. During oogenesis, integral component of the guidance mechanisms that regulate the directional persistent collective migration of the border cell (BC) cluster through the nurse cells to the oocyte. Functions downstream of the two chemoattractant receptors, Pvr and Egfr, to promote BC adhesion between the leader cells of the migrating cluster and the surroundi [...] | 0.796 |
Inx2 | zpg | FBpp0304593 | FBpp0303218 | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | Innexin inx4; Structural component of the gap junctions in germline cells. Required for differentiation and survival of germline cysts in females and of spermatogonia in males; gap junctional communication between spermatogonia and somatic cyst cells may be required for normal differentiation and survival of spermatogonia. Belongs to the pannexin family. | 0.510 |
Inx3 | Inx2 | FBpp0303338 | FBpp0304593 | Innexin 3 (Inx3) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the product of Inx2. Loss of Inx3 leads to the destabilization of the products of ogre, Inx2 and shg at the plasma membrane, suggesting that these four proteins form a complex. | Innexin inx2; Structural components of the gap junctions. Involved in gap junctional communication between germline and somatic cells which is essential for normal oogenesis. In embryonic epidermis, required for epithelial morphogenesis. Required for keyhole formation during early stages of proventriculus development in response to wg signaling. In follicle cells, promotes the formation of egg chambers in part through regulation of shg and baz at the boundary between germ cells and follicle cells. In inner germarial sheath cells, required for survival of early germ cells and for cyst f [...] | 0.742 |
Inx3 | MEP-1 | FBpp0303338 | FBpp0288779 | Innexin 3 (Inx3) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the product of Inx2. Loss of Inx3 leads to the destabilization of the products of ogre, Inx2 and shg at the plasma membrane, suggesting that these four proteins form a complex. | MEP-1, isoform A; MEP-1 (MEP-1) encodes a zinc finger protein that associates with the ATP-dependent nucleosome remodeler encoded by Mi-2. It cooperates with the product of Mi-2 in the repression of cell type-specific genes. | 0.455 |
Inx3 | ogre | FBpp0303338 | FBpp0306903 | Innexin 3 (Inx3) encodes a gap junction protein that can form heteromeric gap junction channels via interaction with the product of Inx2. Loss of Inx3 leads to the destabilization of the products of ogre, Inx2 and shg at the plasma membrane, suggesting that these four proteins form a complex. | Innexin inx1; Optic ganglion reduced (ogre) encodes one of the innexin subunits spanning the membrane 4 times. Together with the products of Inx2 and Inx3, it forms homo or hetero oligomers forming gap junctions, which allow the transfer of small solute between cells. | 0.777 |