STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG32736Small integral membrane protein 4. (79 aa)    
Predicted Functional Partners:
PsGEF
Protostome-specific GEF, isoform E.
      
 0.896
CG12935
LD08826p; It is involved in the biological process described with: nervous system development.
   
  
 0.549
Xbp1
X box binding protein-1 (Xbp1) encodes a transcription factor that mediates the unfolded protein response. Xbp1 mRNA undergoes splicing after being cleaved by the product of Ire1, inducing the expression of ER quality control transcripts. Xbp1 mutants fail to develop beyond the 2nd instar larval stage, indicative of a requirement to resolve inherent ER stress during normal development.
      
 0.493
OXA1L
OXA1L mitochondrial inner membrane protein, isoform A; Membrane insertase activity. It is involved in the biological process described with: protein insertion into mitochondrial inner membrane from matrix; mitochondrial cytochrome c oxidase assembly; respiratory chain complex IV assembly; protein insertion into membrane.
   
  
 0.492
CG1814
FI20020p1; Single-stranded DNA binding; 5'-nucleotidase activity. It is involved in the biological process described with: cellular response to DNA damage stimulus.
      
 0.412
CG10075
RE68357p; It is involved in the biological process described with: mitochondrial respiratory chain complex III assembly; positive regulation of mitochondrial translation.
   
  
 0.404
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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