Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
CG4615LD03007p; It is involved in the biological process described with: cytolysis. (313 aa)    
Predicted Functional Partners:
mei-W68
Meiotic W68 (mei-W68) encodes a protein thought to form a dimer with the TopoVIA subunit encoded by mei-P22 and is required for the formation of double strand breaks during meiosis.
      
 0.816
alpha-Man-Ia
Mannosyl-oligosaccharide alpha-1,2-mannosidase IA; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
   
    0.800
CG31342
FI13065p.
   
    0.797
mbt
Serine/threonine-protein kinase PAK mbt; Involved in neurogenesis of the adult central nervous system, and together with Cdc42, regulates photoreceptor cell morphogenesis. Phosphorylates exogenous substrates when activated by Cdc42.
   
    0.783
CG5790
FI19424p1; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: double-strand break repair via break-induced replication; peptidyl-serine phosphorylation; protein phosphorylation.
      
 0.749
CG7530
LD44720p; Signaling receptor activity.
      
 0.726
RhoGEF2
Rho guanine nucleotide exchange factor 2 (RhoGEF2) encodes a protein involved in actin organization and contractility. It contributes to multiple actin-based processes including wound healing, cell shape and cell contraction.
   
  
 0.701
Nipsnap
Protein NipSnap; Belongs to the NipSnap family.
   
    0.688
CG30394
RE05944p; Amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.
      
 0.671
Galk
Galactokinase, isoform A; Galactokinase (Galk) encodes a protein involved in galactose metabolism that regulates calcineurin-induced cardiac enlargement.
      
 0.671
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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