STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ldsdh1Lipid droplet subset dehydrogenase 1; Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; retinol dehydrogenase activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)    
Predicted Functional Partners:
sturkopf
Lipid droplet-associated hydrolase; Sturkopf (sturkopf) encodes an evolutionary conserved lipid droplet-associated protein. In the absence of lipid droplets, the protein localizes to the endoplasmic reticulum; Belongs to the AB hydrolase superfamily. LDAH family.
    
 
 0.725
yellow-g
FI16876p1.
  
  
 0.615
brun
Protein brunelleschi; Cooperates with Rab11 and fwd/PI4K to mediate the flow of membrane through the Golgi, which is required to support cleavage furrow ingression, therefore promoting cytokinesis in male meiotic cells.
      
 0.599
P5CS
Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.589
CG10672
SD02021p; Carbonyl reductase (NADPH) activity; 3-keto sterol reductase activity; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
  
 
0.517
Pdh
Photoreceptor dehydrogenase (Pdh) encodes a retinal pigment cell dehydrogenase involved in retinol metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.510
CG14984
GEO10764p1.
   
 
 0.508
CG17121
RH48101p; Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
0.495
CG13833
IP10670p; Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
0.490
Eglp4
Entomoglyceroporin 4, isoform F; Water channel activity; channel activity. It is involved in the biological process described with: transmembrane transport; renal system process; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.490
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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