Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG2990 | Fancm | FBpp0071350 | FBpp0306724 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | 0.830 |
| CG2990 | Mcm2 | FBpp0071350 | FBpp0081317 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.433 |
| CG2990 | RPA2 | FBpp0071350 | FBpp0080967 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Replication protein A2, isoform A; Single-stranded DNA binding. It is involved in the biological process described with: double-strand break repair via homologous recombination; DNA repair; DNA replication; nucleotide-excision repair. | 0.893 |
| CG2990 | RPA3 | FBpp0071350 | FBpp0310183 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Replication protein A3 (RPA3) encodes a protein involved in the maintenance of the neuronal stem cell population. | 0.652 |
| CG2990 | Sld5 | FBpp0071350 | FBpp0084348 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Sld5 (Sld5) encodes a subunit of the Cdc45/Mcm2-7/GINS (CMG) complex, which is associated with an ATP-dependent DNA helicase function and is involved in the regulation of the mitotic G1/S transition. | 0.814 |
| CG2990 | hdm | FBpp0071350 | FBpp0071085 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Protein hold'em; Single-stranded DNA-binding protein required for meiosis. May be involved in the resolution of recombination intermediates into crossovers in the meiotic recombination pathway. | 0.914 |
| CG2990 | mei-41 | FBpp0071350 | FBpp0074047 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination. Phosphorylates grp/CHK1. Phosphorylates 'Ser-137' of histone variant H2AX/H2AV at sites of DNA damage, thereby regulating DNA damage response mechanism. [...] | 0.747 |
| CG2990 | mei-9 | FBpp0071350 | FBpp0070624 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | DNA repair endonuclease XPF; Implicated in recombination events during meiosis, mostly in meiotic exchange. May directly resolve Holliday junctions within recombination intermediates leading to DNA exchange. Also required for the repair of mismatches within meiotic heteroduplex DNA and for nucleotide excision repair. | 0.659 |
| CG2990 | mus81 | FBpp0071350 | FBpp0070165 | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | EG:BACR7A4.16 protein; Mus81 (mus81) encodes the catalytic subunit of the Mus81-mms4 structure-selective endonuclease that functions in DNA repair. | 0.942 |
| CG7601 | hdm | FBpp0084910 | FBpp0071085 | Dehydrogenase/reductase SDR family protein 7-like; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Protein hold'em; Single-stranded DNA-binding protein required for meiosis. May be involved in the resolution of recombination intermediates into crossovers in the meiotic recombination pathway. | 0.916 |
| Fancm | CG2990 | FBpp0306724 | FBpp0071350 | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | 0.830 |
| Fancm | RPA2 | FBpp0306724 | FBpp0080967 | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | Replication protein A2, isoform A; Single-stranded DNA binding. It is involved in the biological process described with: double-strand break repair via homologous recombination; DNA repair; DNA replication; nucleotide-excision repair. | 0.587 |
| Fancm | hdm | FBpp0306724 | FBpp0071085 | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | Protein hold'em; Single-stranded DNA-binding protein required for meiosis. May be involved in the resolution of recombination intermediates into crossovers in the meiotic recombination pathway. | 0.887 |
| Fancm | mei-41 | FBpp0306724 | FBpp0074047 | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | Serine/threonine-protein kinase ATR; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination. Phosphorylates grp/CHK1. Phosphorylates 'Ser-137' of histone variant H2AX/H2AV at sites of DNA damage, thereby regulating DNA damage response mechanism. [...] | 0.938 |
| Fancm | mei-9 | FBpp0306724 | FBpp0070624 | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | DNA repair endonuclease XPF; Implicated in recombination events during meiosis, mostly in meiotic exchange. May directly resolve Holliday junctions within recombination intermediates leading to DNA exchange. Also required for the repair of mismatches within meiotic heteroduplex DNA and for nucleotide excision repair. | 0.807 |
| Fancm | mus81 | FBpp0306724 | FBpp0070165 | Fanconi anemia group M helicase (Fancm) encodes a protein that promotes repair of DNA interstrand crosslinks through the Fanconi anemia pathway and non-crossover repair of DNA double-strand breaks. | EG:BACR7A4.16 protein; Mus81 (mus81) encodes the catalytic subunit of the Mus81-mms4 structure-selective endonuclease that functions in DNA repair. | 0.983 |
| Mcm2 | CG2990 | FBpp0081317 | FBpp0071350 | DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | FI06813p; 5'-flap endonuclease activity; RNA binding. It is involved in the biological process described with: DNA replication, Okazaki fragment processing; replication fork reversal. | 0.433 |
| Mcm2 | RPA2 | FBpp0081317 | FBpp0080967 | DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Replication protein A2, isoform A; Single-stranded DNA binding. It is involved in the biological process described with: double-strand break repair via homologous recombination; DNA repair; DNA replication; nucleotide-excision repair. | 0.895 |
| Mcm2 | RPA3 | FBpp0081317 | FBpp0310183 | DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Replication protein A3 (RPA3) encodes a protein involved in the maintenance of the neuronal stem cell population. | 0.645 |
| Mcm2 | Sld5 | FBpp0081317 | FBpp0084348 | DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Sld5 (Sld5) encodes a subunit of the Cdc45/Mcm2-7/GINS (CMG) complex, which is associated with an ATP-dependent DNA helicase function and is involved in the regulation of the mitotic G1/S transition. | 0.999 |
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