Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Hexo2Beta-hexosaminidase; Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism. (622 aa)    
Predicted Functional Partners:
CG7997
Alpha-galactosidase activity. It is involved in the biological process described with: glycosylceramide catabolic process; glycoside catabolic process; oligosaccharide metabolic process.
   
 
 0.962
FucTA
Glycoprotein 3-alpha-L-fucosyltransferase A; Alpha1,3-fucosyltransferase A (FucTA) encodes a Golgi fucosyltransferase that transfers fucose in alpha1,3-linkage to core N-acetylglucosamine residues of N-linked oligosaccharides. It is required for the synthesis of the anti-horseradish peroxidase epitope; Belongs to the glycosyltransferase 10 family.
    
 0.961
CG5731
Alpha-galactosidase activity. It is involved in the biological process described with: oligosaccharide metabolic process; glycoside catabolic process; glycosylceramide catabolic process.
   
 
 0.956
CG7985
BcDNA.GH04120; beta-N-acetylhexosaminidase activity.
     
 0.955
Gal
Beta galactosidase (Gal) encodes a putative digestive enzyme that hydrolyses beta-galactosides into monosaccharides. Gal is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the glycosyl hydrolase 35 family.
  
 
 0.948
Ect3
Beta-galactosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
  
 
 0.944
fdl
Probable beta-hexosaminidase fdl; Involved in brain restructurization via hormonal control during metamorphosis. Implicated in N-glycan processing. Belongs to the glycosyl hydrolase 20 family.
  
  
0.923
Hexo1
Beta-hexosaminidase; Hexosaminidase 1 (Hexo1) encodes a beta-N-acetylglucosaminidase involved in protein deglycosylation and rhodopsin biosynthesis.
  
  
0.919
Cht5
Chitinase 5 (Cht5) encodes an enzyme involved in the formation of chitin-based extracellular matrix at barrier tissues; Belongs to the glycosyl hydrolase 18 family.
    
 0.917
alpha4GT1
Alpha1,4-galactosyltransferase 1; Transferase activity, transferring hexosyl groups; acetylgalactosaminyltransferase activity; alpha-1,4-N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: negative regulation of apoptotic process; glycosphingolipid biosynthetic process; glycolipid biosynthetic process.
     
 0.909
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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