STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Yp2Vitellogenin-2; Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis; Belongs to the AB hydrolase superfamily. Lipase family. (442 aa)    
Predicted Functional Partners:
Yp3
Vitellogenin-3; Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis; Belongs to the AB hydrolase superfamily. Lipase family.
   
0.999
Yp1
Vitellogenin-1; Vitellogenin is the major yolk protein of eggs where it is used as a food source during embryogenesis; Belongs to the AB hydrolase superfamily. Lipase family.
   
0.999
Vm26Aa
Vitelline membrane protein Vm26Aa; Major early eggshell protein; Belongs to the vitelline membrane protein family.
   
  
 0.743
Vm34Ca
Vitelline membrane protein Vm34Ca; Major early eggshell protein; Belongs to the vitelline membrane protein family.
   
  
 0.733
Vm26Ab
Vitelline membrane protein Vm26Ab; Major early eggshell protein.
   
  
 0.635
dsx
Protein doublesex; Controls somatic sexual differentiation. Binds directly and specifically to the FBE (fat body enhancer) of the yolk protein 1 and 2 genes (Yp1 and Yp2). This enhancer is sufficient to direct the female- specific transcription characteristic of the Yp genes in adult fat bodies. Involved in regulation of male-specific expression of takeout in brain-associated fat body.
   
  
 0.603
Cp36
Chorion protein 36 (Cp36) encodes an abundant structural protein of the eggshell whose expression is enhanced by gene amplification in ovarian follicle cells. It is essential for fertility and for endochorion integrity; Belongs to the chorion protein S36 family.
   
  
 0.593
Vm32E
Vitelline membrane 32E (Vm32E) encodes a structural component of the vitelline membrane and the endochorion layer.
   
  
 0.566
Fad2
Fad2 (Fad2) encodes a transmembrane fatty acid desaturase that utilizes mono-unsaturated long-chain fatty acids (LCFAs) to synthesize di-unsaturated LCFAs. It is involved in the synthesis of the female pheromones.
   
  
 0.537
yps
Ypsilon schachtel, isoform A; Nucleic acid binding; protein binding; mRNA binding. It is involved in the biological process described with: oogenesis; mRNA splicing, via spliceosome; regulation of gene expression.
      
 0.533
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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