STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG32683FI20035p1; G protein-coupled receptor binding. It is involved in the biological process described with: G protein-coupled receptor internalization. (804 aa)    
Predicted Functional Partners:
Chc
Clathrin heavy chain (Chc) encodes a protein that forms part of the clathrin complex, which is the major component of coated vesicles.
    
 0.880
CG12640
Uncharacterized protein.
   
  
 0.836
CG15203
Uncharacterized protein, isoform A.
      
 0.796
CG1628
Uncharacterized protein, isoform B; L-ornithine transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport; mitochondrial L-ornithine transmembrane transport; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.790
Gprk2
G protein-coupled receptor kinase 2 (Gprk2) encodes a member of a family of serine/threonine kinases that modulate G-protein coupled receptors. It is required for female fertility, normal egg shape, and normal egg cAMP levels. It is also implicated in Hedgehog signaling and olfactory rhythmicity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
 0.716
CG1545
Uncharacterized protein.
   
  
 0.674
CG43347
Uncharacterized protein, isoform C; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II.
    
 
 0.674
RabX2
CG2885; GTP binding; GTPase activity.
      
 0.666
CG1537
GH02938p.
      
 0.666
mAChR-B
Muscarinic Acetylcholine Receptor, B-type (mAChR-B) encodes a G protein-coupled receptor activated by acetylcholine; Belongs to the G-protein coupled receptor 1 family.
   
 0.654
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.